SCOP 1.73: Domain d2h9gb2: 2h9g B:114-213

Lineage for d2h9gb2 (2h9g B:114-213)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88575] (150 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)

8. Domain d2h9gb2: 2h9g B:114-213 [136258]
   Other proteins in same PDB: d2h9gb1, d2h9gh1, d2h9gr1, d2h9gr2, d2h9gr3
   automatically matched to d1ngzb2

Details for d2h9gb2

PDB Entry: 2h9g, 2.32 Å

PDB Description: Crystal structure of phage derived Fab BdF1 with human Death Receptor 5 (DR5)

PDB Compounds: (B:) Fab BdF1, heavy chain

SCOP Domain Sequences for d2h9gb2:

Sequence, based on SEQRES records:

>d2h9gb2 b.1.1.2 (B:114-213) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

Sequence, based on observed residues (ATOM records):

>d2h9gb2 b.1.1.2 (B:114-213) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapssgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysl
ssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

Timeline for d2h9gb2:

• d2h9gb2 is new in SCOP 1.73
  
• d2h9gb2 appears in SCOP 1.75
  
• d2h9gb2 appears in the current release, SCOPe 2.08