SCOPe 2.03: Domain d2gywb_: 2gyw B:

Lineage for d2gywb_ (2gyw B:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Acetylcholinesterase [53476] (5 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [53479] (17 PDB entries)

8. Domain d2gywb_: 2gyw B: [135878]
   automated match to d1maac_
   complexed with co3, nag, obi, p6g

Details for d2gywb_

PDB Entry: 2gyw, 2.4 Å

PDB Description: crystal structure of mus musculus acetylcholinesterase in complex with obidoxime

PDB Compounds: (B:) acetylcholinesterase

SCOPe Domain Sequences for d2gywb_:

Sequence, based on SEQRES records:

>d2gywb_ c.69.1.1 (B:) Acetylcholinesterase {Mouse (Mus musculus) [TaxId: 10090]}
edpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvldat
tfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiygggf
ysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlalqwv
qeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvsage
arrratllarlvgcppggaggndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvv
dgdflsdtpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagv
rigvpqasdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqga
rvyayifehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnf
artgdpndprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkllsat

Sequence, based on observed residues (ATOM records):

>d2gywb_ c.69.1.1 (B:) Acetylcholinesterase {Mouse (Mus musculus) [TaxId: 10090]}
edpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvldat
tfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiygggf
ysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlalqwv
qeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvsage
arrratllarlvgcndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvvdgdflsd
tpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagvrigvpqa
sdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqgarvyayif
ehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnfartgdpn
dprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkllsat

Timeline for d2gywb_:

• d2gywb_ first appeared in SCOP 1.73, called d2gywb1
  
• d2gywb_ appears in SCOPe 2.02
  
• d2gywb_ appears in SCOPe 2.04
  
• d2gywb_ appears in the current release, SCOPe 2.08