SCOP 1.73: Domain d2guoa2: 2guo A:1-181

Lineage for d2guoa2 (2guo A:1-181)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
   dimeric

4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (1 family)

5. Family d.19.1.1: MHC antigen-recognition domain [54453] (12 proteins)

6. Protein Class I MHC, alpha-1 and alpha-2 domains [54468] (22 species)

7. Species Human (Homo sapiens), HLA-A2.1 [TaxId:9606] [54470] (62 PDB entries)

8. Domain d2guoa2: 2guo A:1-181 [135739]
   Other proteins in same PDB: d2guoa1, d2guob1, d2guod1, d2guoe1
   automatically matched to d1akja2
   complexed with gol, na

Details for d2guoa2

PDB Entry: 2guo, 1.9 Å

PDB Description: Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide

PDB Compounds: (A:) HLA class I histocompatibility antigen, A-2 alpha chain

SCOP Domain Sequences for d2guoa2:

Sequence; same for both SEQRES and ATOM records:

>d2guoa2 d.19.1.1 (A:1-181) Class I MHC, alpha-1 and alpha-2 domains {Human (Homo sapiens), HLA-A2.1 [TaxId: 9606]}
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
r

Timeline for d2guoa2:

• d2guoa2 is new in SCOP 1.73
  
• d2guoa2 appears in SCOP 1.75
  
• d2guoa2 appears in the current release, SCOPe 2.08