SCOPe 2.01: Domain d2gpua_: 2gpu A:

Lineage for d2gpua_ (2gpu A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Orphan nuclear receptor ERR3 [81916] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [81917] (13 PDB entries)
   Uniprot O75454 233-458

8. Domain d2gpua_: 2gpu A: [135493]
   automated match to d1tfca_
   complexed with oht

Details for d2gpua_

PDB Entry: 2gpu, 1.7 Å

PDB Description: estrogen related receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen

PDB Compounds: (A:) Estrogen-related receptor gamma

SCOPe Domain Sequences for d2gpua_:

Sequence; same for both SEQRES and ATOM records:

>d2gpua_ a.123.1.1 (A:) Orphan nuclear receptor ERR3 {Human (Homo sapiens) [TaxId: 9606]}
ynkivshllvaepekiyampdptvpdsdikalttlcdladrelvviigwakhipgfstls
ladqmsllqsawmeililgvvyrslsfedelvyaddyimdedqsklaglldlnnailqlv
kkyksmklekeefvtlkaialansdsmhiedveavqklqdvlhealqdyeagqhmedprr
agkmlmtlpllrqtstkavqhfyniklegkvpmhklflemle

Timeline for d2gpua_:

• d2gpua_ first appeared in SCOP 1.73, called d2gpua1
  
• d2gpua_ was called d2gpua1 in SCOP 1.75
  
• d2gpua_ appears in SCOPe 2.02
  
• d2gpua_ appears in the current release, SCOPe 2.08