SCOP 1.75: Domain d2gpua1: 2gpu A:235-455

Lineage for d2gpua1 (2gpu A:235-455)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Orphan nuclear receptor ERR3 [81916] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [81917] (16 PDB entries)
   Uniprot O75454 233-458

8. Domain d2gpua1: 2gpu A:235-455 [135493]
   automatically matched to d1tfca_
   complexed with oht

Details for d2gpua1

PDB Entry: 2gpu, 1.7 Å

PDB Description: estrogen related receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen

PDB Compounds: (A:) Estrogen-related receptor gamma

SCOP Domain Sequences for d2gpua1:

Sequence; same for both SEQRES and ATOM records:

>d2gpua1 a.123.1.1 (A:235-455) Orphan nuclear receptor ERR3 {Human (Homo sapiens) [TaxId: 9606]}
nkivshllvaepekiyampdptvpdsdikalttlcdladrelvviigwakhipgfstlsl
adqmsllqsawmeililgvvyrslsfedelvyaddyimdedqsklaglldlnnailqlvk
kyksmklekeefvtlkaialansdsmhiedveavqklqdvlhealqdyeagqhmedprra
gkmlmtlpllrqtstkavqhfyniklegkvpmhklflemle

Timeline for d2gpua1:

• d2gpua1 first appeared in SCOP 1.73
  
• d2gpua1 is called d2gpua_ in SCOPe 2.01
  
• d2gpua1 appears in the current release, SCOPe 2.08, called d2gpua_