SCOP 1.73: Domain d2gm1d1: 2gm1 D:18-362

Lineage for d2gm1d1 (2gm1 D:18-362)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.9: Motor proteins [52641] (4 proteins)

6. Protein Kinesin [52646] (7 species)

7. Species Human (Homo sapiens), mitotic kinesin eg5 [TaxId:9606] [64018] (14 PDB entries)

8. Domain d2gm1d1: 2gm1 D:18-362 [135352]
   automatically matched to d1q0bb_
   complexed with 2az, adp, mg

Details for d2gm1d1

PDB Entry: 2gm1, 2.3 Å

PDB Description: crystal structure of the mitotic kinesin eg5 in complex with mg-adp and n-(3-aminopropyl)-n-((3-benzyl-5-chloro-4-oxo-3,4- dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)(cyclopropyl)methyl)-4- methylbenzamide

PDB Compounds: (D:) kinesin-related motor protein eg5

SCOP Domain Sequences for d2gm1d1:

Sequence, based on SEQRES records:

>d2gm1d1 c.37.1.9 (D:18-362) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviik
gleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvk
igklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyresklt
rilqdslggrtrtsiiatispaslnleetlstleyahraknilnk

Sequence, based on observed residues (ATOM records):

>d2gm1d1 c.37.1.9 (D:18-362) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtgglkssrktytfdmvfgastkqi
dvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprt
lhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikgl
eeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkvkigklnlvdlag
seninqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiatispaslnle
etlstleyahraknilnk

Timeline for d2gm1d1:

• d2gm1d1 is new in SCOP 1.73
  
• d2gm1d1 appears in SCOP 1.75
  
• d2gm1d1 appears in the current release, SCOPe 2.08, called d2gm1d_