SCOPe 2.06: Domain d2ghwa_: 2ghw A:

Lineage for d2ghwa_ (2ghw A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.318: SARS receptor-binding domain-like [143586] (1 superfamily)
   core: 3 layers, a/b/a; antiparallel beta-sheet of 5 strands, order 13542

4. Superfamily d.318.1: SARS receptor-binding domain-like [143587] (1 family)
   automatically mapped to Pfam PF09408

5. Family d.318.1.1: SARS receptor-binding domain-like [143588] (2 proteins)
   part of PfamB PB000266

6. Protein Spike protein S1 [143589] (1 species)

7. Species SARS coronavirus [TaxId:227859] [143590] (8 PDB entries)
   Uniprot P59594 320-502! Uniprot P59594 321-512! Uniprot P59594 323-502

8. Domain d2ghwa_: 2ghw A: [135216]
   Other proteins in same PDB: d2ghwb1, d2ghwb2, d2ghwd1, d2ghwd2
   automated match to d2dd8s1
   complexed with cl

Details for d2ghwa_

PDB Entry: 2ghw, 2.3 Å

PDB Description: Crystal structure of SARS spike protein receptor binding domain in complex with a neutralizing antibody, 80R

PDB Compounds: (A:) Spike glycoprotein

SCOPe Domain Sequences for d2ghwa_:

Sequence; same for both SEQRES and ATOM records:

>d2ghwa_ d.318.1.1 (A:) Spike protein S1 {SARS coronavirus [TaxId: 227859]}
itnlcpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklndlc
fsnvyadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnyny
kyrylrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvv
lsfellnapat

Timeline for d2ghwa_:

• d2ghwa_ first appeared in SCOP 1.73, called d2ghwa1
  
• d2ghwa_ appears in SCOPe 2.05
  
• d2ghwa_ appears in SCOPe 2.07
  
• d2ghwa_ appears in the current release, SCOPe 2.08