SCOPe 2.03: Domain d2fx4a_: 2fx4 A:

Lineage for d2fx4a_ (2fx4 A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Trypsin(ogen) [50515] (9 species)

7. Species Cow (Bos taurus) [TaxId:9913] [50516] (392 PDB entries)
   Uniprot P00760

8. Domain d2fx4a_: 2fx4 A: [134274]
   automated match to d1aq7__
   complexed with c1r, ca

Details for d2fx4a_

PDB Entry: 2fx4, 1.65 Å

PDB Description: bovine trypsin bound by 4-piperidinebutyrate to make acylenzyme complex

PDB Compounds: (A:) Trypsin

SCOPe Domain Sequences for d2fx4a_:

Sequence; same for both SEQRES and ATOM records:

>d2fx4a_ b.47.1.2 (A:) Trypsin(ogen) {Cow (Bos taurus) [TaxId: 9913]}
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsntlnndimliklksaaslnsrvasislptscasagtqclisg
wgntkssgtsypdvlkclkapilsdsscksaypgqitsnmfcagyleggkdscqgdsggp
vvcsgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn

Timeline for d2fx4a_:

• d2fx4a_ first appeared in SCOP 1.73, called d2fx4a1
  
• d2fx4a_ appears in SCOPe 2.02
  
• d2fx4a_ appears in SCOPe 2.04
  
• d2fx4a_ appears in the current release, SCOPe 2.08