SCOPe 2.01: Domain d2fumd1: 2fum D:3-277

Lineage for d2fumd1 (2fum D:3-277)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Mycobacterial protein kinase PknB, catalytic domain [82793] (1 species)
   OPK group; PKN subfamily; serine/threonine kinase

7. Species Mycobacterium tuberculosis [TaxId:1773] [82794] (3 PDB entries)

8. Domain d2fumd1: 2fum D:3-277 [134179]
   automatically matched to d1mrub_
   complexed with mix

Details for d2fumd1

PDB Entry: 2fum, 2.89 Å

PDB Description: Catalytic domain of protein kinase PknB from Mycobacterium tuberculosis in complex with mitoxantrone

PDB Compounds: (D:) Probable serine/threonine-protein kinase pknB

SCOPe Domain Sequences for d2fumd1:

Sequence, based on SEQRES records:

>d2fumd1 d.144.1.7 (D:3-277) Mycobacterial protein kinase PknB, catalytic domain {Mycobacterium tuberculosis [TaxId: 1773]}
tpshlsdryelgeilgfggmsevhlardlrlhrdvavkvlradlardpsfylrfrreaqn
aaalnhpaivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviada
cqalnfshqngiihrdvkpanimisatnavkvmdfgiaraiadsgnsvtqtaavigtaqy
lspeqargdsvdarsdvyslgcvlyevltgeppftgdspvsvayqhvredpippsarheg
lsadldavvlkalaknpenryqtaaemradlvrvh

Sequence, based on observed residues (ATOM records):

>d2fumd1 d.144.1.7 (D:3-277) Mycobacterial protein kinase PknB, catalytic domain {Mycobacterium tuberculosis [TaxId: 1773]}
tpshlsdryelgeilgfggmsevhlardlrlhrdvavkvlradlardpsfylrfrreaqn
aaalnhpaivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviada
cqalnfshqngiihrdvkpanimisatnavkvmdfgiigtaqylspeqargdsvdarsdv
yslgcvlyevltgeppftgdspvsvayqhvredpippsarheglsadldavvlkalaknp
enryqtaaemradlvrvh

Timeline for d2fumd1:

• d2fumd1 first appeared in SCOP 1.73
  
• d2fumd1 appears in SCOP 1.75
  
• d2fumd1 appears in SCOPe 2.02
  
• d2fumd1 appears in the current release, SCOPe 2.08, called d2fumd_