SCOPe 2.01: Domain d2frhb_: 2frh B:

Lineage for d2frhb_ (2frh B:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (85 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.28: MarR-like transcriptional regulators [63379] (20 proteins)
   The N- and C-terminal helical extensions to the common fold form the dimer interface

6. Protein Pleiotropic regulator of virulence genes, SarA [48292] (1 species)
   closely related to SarR but adopts a different fold; possible experimental artifact?

7. Species Staphylococcus aureus [TaxId:1280] [48293] (3 PDB entries)

8. Domain d2frhb_: 2frh B: [133989]
   automated match to d1fzpb_
   complexed with ca

Details for d2frhb_

PDB Entry: 2frh, 2.5 Å

PDB Description: Crystal Structure of Sara, A Transcription Regulator From Staphylococcus Aureus

PDB Compounds: (B:) Staphylococcal accessory regulator A

SCOPe Domain Sequences for d2frhb_:

Sequence; same for both SEQRES and ATOM records:

>d2frhb_ a.4.5.28 (B:) Pleiotropic regulator of virulence genes, SarA {Staphylococcus aureus [TaxId: 1280]}
gshmaitkindcfellsmvtyadklkslikkefsisfeefavltyisenkekeyylkdii
nhlnykqpqvvkavkilsqedyfdkkrnehdertvlilvnaqqrkkiesllsrvnkrite
anneiel

Timeline for d2frhb_:

• d2frhb_ first appeared in SCOP 1.73, called d2frhb1
  
• d2frhb_ was called d2frhb1 in SCOP 1.75
  
• d2frhb_ appears in SCOPe 2.02
  
• d2frhb_ appears in the current release, SCOPe 2.08, called d2frhb2