SCOPe 2.02: Domain d2feeo2: 2fee O:107-210

Lineage for d2feeo2 (2fee O:107-210)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (134 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d2feeo2: 2fee O:107-210 [133342]
   Other proteins in same PDB: d2feea1, d2feeb1, d2feel1, d2feeo1
   automatically matched to d1dqdl2

Details for d2feeo2

PDB Entry: 2fee, 3.2 Å

PDB Description: Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr

PDB Compounds: (O:) Fab fragment, light chain

SCOPe Domain Sequences for d2feeo2:

Sequence; same for both SEQRES and ATOM records:

>d2feeo2 b.1.1.2 (O:107-210) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnr

Timeline for d2feeo2:

• d2feeo2 first appeared in SCOP 1.73
  
• d2feeo2 appears in SCOPe 2.01
  
• d2feeo2 appears in SCOPe 2.03
  
• d2feeo2 appears in the current release, SCOPe 2.08