SCOPe 2.04: Domain d2fcia1: 2fci A:1-105

Lineage for d2fcia1 (2fci A:1-105)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Phospholipase C-gamma-1 [55577] (2 species)

7. Species Cow (Bos taurus) [TaxId:9913] [55578] (3 PDB entries)

8. Domain d2fcia1: 2fci A:1-105 [133268]
   automatically matched to d2plda_

Details for d2fcia1

PDB Entry: 2fci

PDB Description: Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase

PDB Compounds: (A:) C-termainl SH2 domain from phospholipase C-gamma-1 comprising residues 663-759

SCOPe Domain Sequences for d2fcia1:

Sequence; same for both SEQRES and ATOM records:

>d2fcia1 d.93.1.1 (A:1-105) Phospholipase C-gamma-1 {Cow (Bos taurus) [TaxId: 9913]}
gspgiheskewyhasltraqaehmlmrvprdgaflvrkrnepnsyaisfraegkikhcrv
qqegqtvmlgnsefdslvdlisyyekhplyrkmklrypineenss

Timeline for d2fcia1:

• d2fcia1 first appeared in SCOP 1.73
  
• d2fcia1 appears in SCOPe 2.03
  
• d2fcia1 appears in SCOPe 2.05
  
• d2fcia1 appears in the current release, SCOPe 2.08