SCOPe 2.03: Domain d2f7sa1: 2f7s A:5-190

Lineage for d2f7sa1 (2f7s A:5-190)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rab27b [142263] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142264] (1 PDB entry)
   Uniprot O00194 4-189

8. Domain d2f7sa1: 2f7s A:5-190 [133104]
   complexed with gdp, mg

Details for d2f7sa1

PDB Entry: 2f7s, 2.7 Å

PDB Description: The crystal structure of human Rab27b bound to GDP

PDB Compounds: (A:) Ras-related protein Rab-27B

SCOPe Domain Sequences for d2f7sa1:

Sequence, based on SEQRES records:

>d2f7sa1 c.37.1.8 (A:5-190) Rab27b {Human (Homo sapiens) [TaxId: 9606]}
dydylikllalgdsgvgkttflyrytdnkfnpkfittvgidfrekrvvynaqgpngssgk
afkvhlqlwdtagqerfrslttaffrdamgfllmfdltsqqsflnvrnwmsqlqanayce
npdivlignkadlpdqrevnerqareladkygipyfetsaatgqnvekavetlldlimkr
meqcve

Sequence, based on observed residues (ATOM records):

>d2f7sa1 c.37.1.8 (A:5-190) Rab27b {Human (Homo sapiens) [TaxId: 9606]}
dydylikllalgdsgvgkttflyrytdnkfnpkfittvgidfrekrvvynagkafkvhlq
lwdtagqerfrslttaffrdamgfllmfdltsqqsflnvrnwmsqlqanaycenpdivli
gnkadlpdqrevnerqareladkygipyfetsaatgqnvekavetlldlimkrmeqcve

Timeline for d2f7sa1:

• d2f7sa1 first appeared in SCOP 1.73
  
• d2f7sa1 appears in SCOPe 2.02
  
• d2f7sa1 appears in SCOPe 2.04
  
• d2f7sa1 appears in the current release, SCOPe 2.08