SCOPe 2.01: Domain d2f66f_: 2f66 F:

Lineage for d2f66f_ (2f66 F:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.2: Long alpha-hairpin [46556] (20 superfamilies)
   2 helices; antiparallel hairpin, left-handed twist

4. Superfamily a.2.17: Endosomal sorting complex assembly domain [140111] (3 families)
   forms 'fan'-like heterooligomers, in which the domains of different subunit make similar interactions at the tip of the hairpin

5. Family a.2.17.3: VPS37 C-terminal domain-like [140118] (1 protein)
   Pfam PF07200; Modifier of rudimentary, Mod(r)

6. Protein Vacuolar protein sorting-associated protein 37, VPS37 (SRN2) [140119] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [140120] (2 PDB entries)
   Uniprot Q99176 139-203! Uniprot Q99176 142-206

8. Domain d2f66f_: 2f66 F: [133032]
   Other proteins in same PDB: d2f66a1, d2f66b1, d2f66d_, d2f66e_
   automated match to d2f66c1
   complexed with so4

Details for d2f66f_

PDB Entry: 2f66, 2.8 Å

PDB Description: structure of the escrt-i endosomal trafficking complex

PDB Compounds: (F:) protein srn2

SCOPe Domain Sequences for d2f66f_:

Sequence; same for both SEQRES and ATOM records:

>d2f66f_ a.2.17.3 (F:) Vacuolar protein sorting-associated protein 37, VPS37 (SRN2) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
ygdialkkkleqntkkldeessqletttrsidsaddldqfiknyldirtqyhlrreklat
wdk

Timeline for d2f66f_:

• d2f66f_ first appeared in SCOP 1.73, called d2f66f1
  
• d2f66f_ was called d2f66f1 in SCOP 1.75
  
• d2f66f_ appears in SCOPe 2.02
  
• d2f66f_ appears in the current release, SCOPe 2.08