SCOP 1.75: Domain d2f66f1: 2f66 F:145-206

Lineage for d2f66f1 (2f66 F:145-206)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.2: Long alpha-hairpin [46556] (20 superfamilies)
   2 helices; antiparallel hairpin, left-handed twist

4. Superfamily a.2.17: Endosomal sorting complex assembly domain [140111] (3 families)
   forms 'fan'-like heterooligomers, in which the domains of different subunit make similar interactions at the tip of the hairpin

5. Family a.2.17.3: VPS37 C-terminal domain-like [140118] (1 protein)
   Pfam PF07200; Modifier of rudimentary, Mod(r)

6. Protein Vacuolar protein sorting-associated protein 37, VPS37 (SRN2) [140119] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [140120] (2 PDB entries)
   Uniprot Q99176 139-203! Uniprot Q99176 142-206

8. Domain d2f66f1: 2f66 F:145-206 [133032]
   Other proteins in same PDB: d2f66a1, d2f66b1, d2f66d1, d2f66e1
   automatically matched to 2F66 C:142-206
   complexed with so4; mutant

Details for d2f66f1

PDB Entry: 2f66, 2.8 Å

PDB Description: structure of the escrt-i endosomal trafficking complex

PDB Compounds: (F:) protein srn2

SCOP Domain Sequences for d2f66f1:

Sequence; same for both SEQRES and ATOM records:

>d2f66f1 a.2.17.3 (F:145-206) Vacuolar protein sorting-associated protein 37, VPS37 (SRN2) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
ygdialkkkleqntkkldeessqletttrsidsaddldqfiknyldirtqyhlrreklat
wd

Timeline for d2f66f1:

• d2f66f1 first appeared in SCOP 1.73
  
• d2f66f1 is called d2f66f_ in SCOPe 2.01
  
• d2f66f1 appears in the current release, SCOPe 2.08, called d2f66f_