Lineage for d2f54a1 (2f54 A:182-274)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 783929Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 784408Protein Class I MHC, alpha-3 domain [88604] (4 species)
  7. 784409Species Human (Homo sapiens) [TaxId:9606] [88605] (157 PDB entries)
    Uniprot P30685 25-300
    Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor
    Uniprot P30481 25-300
    Uniprot P01892 25-298
    Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 alpha chain precursor
    Uniprot P30685 25-300 ! Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor ! Uniprot P30481 25-300 ! Uniprot P01892 25-298 ! Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 alpha chain precursor
  8. 784566Domain d2f54a1: 2f54 A:182-274 [132968]
    Other proteins in same PDB: d2f54a2, d2f54b1, d2f54d1, d2f54d2, d2f54e1, d2f54e2, d2f54f2, d2f54g1, d2f54k1, d2f54k2, d2f54l1, d2f54l2
    automatically matched to d1akja1
    mutant

Details for d2f54a1

PDB Entry: 2f54 (more details), 2.7 Å

PDB Description: Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity
PDB Compounds: (A:) hla class I histocompatibility antigen

SCOP Domain Sequences for d2f54a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2f54a1 b.1.1.2 (A:182-274) Class I MHC, alpha-3 domain {Human (Homo sapiens) [TaxId: 9606]}
tdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgtf
qkwaavvvpsgqeqrytchvqheglpkpltlrw

SCOP Domain Coordinates for d2f54a1:

Click to download the PDB-style file with coordinates for d2f54a1.
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Timeline for d2f54a1: