Lineage for d2f2cb1 (2f2c B:10-305)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874749Protein Cyclin-dependent PK, CDK6 [88859] (1 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 874750Species Human (Homo sapiens) [TaxId:9606] [88860] (8 PDB entries)
  8. 874754Domain d2f2cb1: 2f2c B:10-305 [132807]
    Other proteins in same PDB: d2f2ca1, d2f2ca2
    automatically matched to d1blxa_
    complexed with ap9, dms, so4

Details for d2f2cb1

PDB Entry: 2f2c (more details), 2.8 Å

PDB Description: x-ray structure of human cdk6-vcyclinwith the inhibitor aminopurvalanol
PDB Compounds: (B:) cell division protein kinase 6

SCOP Domain Sequences for d2f2cb1:

Sequence, based on SEQRES records: (download)

>d2f2cb1 d.144.1.7 (B:10-305) Cyclin-dependent PK, CDK6 {Human (Homo sapiens) [TaxId: 9606]}
dqqyecvaeigegaygkvfkardlknggrfvalkrvrvqtgeegmplstirevavlrhle
tfehpnvvrlfdvctvsrtdretkltlvfehvdqdlttyldkvpepgvptetikdmmfql
lrgldflhshrvvhrdlkpqnilvtssgqikladfglariysfqmaltsvvvtlwyrape
vllqssyatpvdlwsvgcifaemfrrkplfrgssdvdqlgkildviglpgeedwprdval
prqafhsksaqpiekfvtdidelgkdlllkcltfnpakrisaysalshpyfqdler

Sequence, based on observed residues (ATOM records): (download)

>d2f2cb1 d.144.1.7 (B:10-305) Cyclin-dependent PK, CDK6 {Human (Homo sapiens) [TaxId: 9606]}
dqqyecaeiggkvfkardlknggrfvalkrvrvqtgeegmplstirevavlrhletfehp
nvvrlfdvctvstdretkltlvfehvdqdlttyldkvpepgvptetikdmmfqllrgldf
lhshrvvhrdlkpqnilvtssgqikladfglariysfqmaltsvvvtlwyrapevllqss
yatpvdlwsvgcifaemfrrkplfrgssdvdqlgkildviglpgeedwpqafaqpiekfv
tdidelgkdlllkcltfnpakrisaysalshpyfqdler

SCOP Domain Coordinates for d2f2cb1:

Click to download the PDB-style file with coordinates for d2f2cb1.
(The format of our PDB-style files is described here.)

Timeline for d2f2cb1: