Lineage for d2f16v1 (2f16 V:1-223)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 875596Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 875597Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (7 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 875747Family d.153.1.4: Proteasome subunits [56251] (3 proteins)
  6. 876137Protein Proteasome beta subunit (catalytic) [56252] (5 species)
  7. 876210Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (12 PDB entries)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
  8. 876290Domain d2f16v1: 2f16 V:1-223 [132712]
    Other proteins in same PDB: d2f16a1, d2f16b1, d2f16c1, d2f16d1, d2f16e1, d2f16f1, d2f16g1, d2f16o1, d2f16p1, d2f16q1, d2f16r1, d2f16s1, d2f16t1, d2f16u1
    automatically matched to d1g0uh_
    complexed with bo2

Details for d2f16v1

PDB Entry: 2f16 (more details), 2.8 Å

PDB Description: Crystal structure of the yeast 20S proteasome in complex with bortezomib
PDB Compounds: (V:) Proteasome component PUP1

SCOP Domain Sequences for d2f16v1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2f16v1 d.153.1.4 (V:1-223) Proteasome beta subunit (catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcagagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivnicd

SCOP Domain Coordinates for d2f16v1:

Click to download the PDB-style file with coordinates for d2f16v1.
(The format of our PDB-style files is described here.)

Timeline for d2f16v1: