SCOPe 2.03: Domain d2dtsa1: 2dts A:234-341

Lineage for d2dtsa1 (2dts A:234-341)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma [88584] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88585] (33 PDB entries)
   Uniprot P01857 #118-327 ! Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region

8. Domain d2dtsa1: 2dts A:234-341 [131729]
   Other proteins in same PDB: d2dtsa2, d2dtsb2
   automated match to d1igyb3
   complexed with nag

Details for d2dtsa1

PDB Entry: 2dts, 2.2 Å

PDB Description: crystal structure of the defucosylated fc fragment from human immunoglobulin g1

PDB Compounds: (A:) Ig gamma-1 chain C region

SCOPe Domain Sequences for d2dtsa1:

Sequence; same for both SEQRES and ATOM records:

>d2dtsa1 b.1.1.2 (A:234-341) Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma {Human (Homo sapiens) [TaxId: 9606]}
llggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpre
eqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakg

Timeline for d2dtsa1:

• d2dtsa1 first appeared in SCOP 1.73
  
• d2dtsa1 appears in SCOPe 2.02
  
• d2dtsa1 appears in SCOPe 2.04
  
• d2dtsa1 appears in the current release, SCOPe 2.08