SCOP 1.75: Domain d2dqyb1: 2dqy B:2021-2553

Lineage for d2dqyb1 (2dqy B:2021-2553)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (41 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (5 proteins)

6. Protein Mammalian carboxylesterase (liver carboxylesterase I) [75282] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89768] (13 PDB entries)

8. Domain d2dqyb1: 2dqy B:2021-2553 [131645]
   automatically matched to d1mx9d_
   complexed with chd, nag, plm, sia, so4

Details for d2dqyb1

PDB Entry: 2dqy, 3 Å

PDB Description: crystal structure of human carboxylesterase in complex with cholate and palmitate

PDB Compounds: (B:) Liver carboxylesterase 1

SCOP Domain Sequences for d2dqyb1:

Sequence; same for both SEQRES and ATOM records:

>d2dqyb1 c.69.1.1 (B:2021-2553) Mammalian carboxylesterase (liver carboxylesterase I) {Human (Homo sapiens) [TaxId: 9606]}
ssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvkna
tsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwih
ggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrw
vqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgd
vkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllg
tvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsl
lwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdag
aptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwa
nfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

Timeline for d2dqyb1:

• d2dqyb1 first appeared in SCOP 1.73
  
• d2dqyb1 appears in SCOPe 2.01
  
• d2dqyb1 appears in the current release, SCOPe 2.08, called d2dqyb_