SCOP 1.75: Domain d2csba4: 2csb A:465-519

Lineage for d2csba4 (2csb A:465-519)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.60: SAM domain-like [47768] (16 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.2: RuvA domain 2-like [47781] (7 families)
   duplication: contains two helix-hairpin-helix (HhH) motifs

5. Family a.60.2.4: Topoisomerase V repeat domain [140626] (1 protein)
   this is a repeat family; one repeat unit is 2csb A:351-409 found in domain

6. Protein Topoisomerase V [140627] (1 species)

7. Species Methanopyrus kandleri [TaxId:2320] [140628] (1 PDB entry)
   Uniprot Q977W1 294-350! Uniprot Q977W1 351-409! Uniprot Q977W1 410-464! Uniprot Q977W1 465-519

8. Domain d2csba4: 2csb A:465-519 [130754]
   Other proteins in same PDB: d2csba5
   4th repeat
   complexed with mg

Details for d2csba4

PDB Entry: 2csb, 2.3 Å

PDB Description: crystal structure of topoisomerase v from methanopyrus kandleri (61 kda fragment)

PDB Compounds: (A:) Topoisomerase V

SCOP Domain Sequences for d2csba4:

Sequence; same for both SEQRES and ATOM records:

>d2csba4 a.60.2.4 (A:465-519) Topoisomerase V {Methanopyrus kandleri [TaxId: 2320]}
pgyaslisirgidreraerllkkyggyskvreagveelredgltdaqirelkglk

Timeline for d2csba4:

• d2csba4 first appeared in SCOP 1.73
  
• d2csba4 appears in SCOPe 2.01
  
• d2csba4 appears in the current release, SCOPe 2.08