SCOPe 2.08: Domain d2cnbc_: 2cnb C:

Lineage for d2cnbc_ (2cnb C:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein automated matches [190085] (59 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [187036] (1 PDB entry)

8. Domain d2cnbc_: 2cnb C: [130638]
   automated match to d1gy8a_
   complexed with nad, ufg

Details for d2cnbc_

PDB Entry: 2cnb, 2.7 Å

PDB Description: trypanosoma brucei udp-galactose-4-epimerase in ternary complex with nad and the substrate analogue udp-4-deoxy-4-fluoro-alpha-d-galactose

PDB Compounds: (C:) udp-galactose-4-epimerase

SCOPe Domain Sequences for d2cnbc_:

Sequence, based on SEQRES records:

>d2cnbc_ c.2.1.2 (C:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptmgsvstnaepidinakkspespygeskl
iaermirdcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiapdq
rltihedastdkrmpifgtdyptpdgtcvrdyvhvcdlasahilaldyveklgpndksky
fsvfnlgtsrgysvrevievarkttghpipvrecgrregdpaylvaasdkarevlgwkpk
ydtleaimetswkfqrthpngya

Sequence, based on observed residues (ATOM records):

>d2cnbc_ c.2.1.2 (C:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
shmrvlvcggagyigshfvrallrdtnhsvvivdslvgthgksdhvetrenvarklqqsd
gpkppwadryaalevgdvrnedflngvftrhgpidavvhmcaflavgesvrdplkyydnn
vvgilrllqamllhkcdkiifsssaaifgnptaepidinakkspespygeskliaermir
dcaeaygikgiclryfnacgahedgdigehyqgsthlipiilgrvmsdiapdtdkrmpif
gtdyptpdgtcvrdyvhvcdlasahilaldyveklgpndkskyfsvfnlgtsrgysvrev
ievarkttghpipvrecgrregdpaylvaasdkarevlgwkpkydtleaimetswkfqrt
hpngya

Timeline for d2cnbc_:

• d2cnbc_ first appeared in SCOP 1.73, called d2cnbc1
  
• d2cnbc_ appears in SCOPe 2.07