SCOP 1.73: Domain d2c6ga3: 2c6g A:57-117,A:351-593

Lineage for d2c6ga3 (2c6g A:57-117,A:351-593)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.56: Phosphorylase/hydrolase-like [53162] (7 superfamilies)
   core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops

4. Superfamily c.56.5: Zn-dependent exopeptidases [53187] (8 families)
   core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest

5. Family c.56.5.5: FolH catalytic domain-like [53210] (2 proteins)

6. Protein Glutamate carboxypeptidase II FOLH1 [142522] (1 species)
   Folate hydrolase 1, FolH homologue

7. Species Human (Homo sapiens) [TaxId:9606] [142523] (11 PDB entries)

8. Domain d2c6ga3: 2c6g A:57-117,A:351-593 [129994]
   Other proteins in same PDB: d2c6ga1, d2c6ga2
   automatically matched to 2C6C A:57-117,A:351-593
   complexed with bma, ca, cl, glu, man, nag, zn

Details for d2c6ga3

PDB Entry: 2c6g, 2.2 Å

PDB Description: membrane-bound glutamate carboxypeptidase ii (gcpii) with bound glutamate

PDB Compounds: (A:) glutamate carboxypeptidase II

SCOP Domain Sequences for d2c6ga3:

Sequence, based on SEQRES records:

>d2c6ga3 c.56.5.5 (A:57-117,A:351-593) Glutamate carboxypeptidase II FOLH1 {Human (Homo sapiens) [TaxId: 9606]}
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lXevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkke
gwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctp
lmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrl
giasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfela
nsivl

Sequence, based on observed residues (ATOM records):

>d2c6ga3 c.56.5.5 (A:57-117,A:351-593) Glutamate carboxypeptidase II FOLH1 {Human (Homo sapiens) [TaxId: 9606]}
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lXevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkke
gwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctp
lmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrl
giasgrarytkngyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivl

Timeline for d2c6ga3:

• d2c6ga3 is new in SCOP 1.73
  
• d2c6ga3 appears in SCOP 1.75
  
• d2c6ga3 appears in the current release, SCOPe 2.08