SCOPe 2.03: Domain d2c4ga_: 2c4g A:

Lineage for d2c4ga_ (2c4g A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)

8. Domain d2c4ga_: 2c4g A: [129809]
   Other proteins in same PDB: d2c4gb1, d2c4gb2, d2c4gd1, d2c4gd2
   automated match to d1vywa_
   complexed with 514, so4

Details for d2c4ga_

PDB Entry: 2c4g, 2.7 Å

PDB Description: structure of cdk2-cyclin a with pha-533514

PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d2c4ga_:

Sequence; same for both SEQRES and ATOM records:

>d2c4ga_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
plvdmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllk
elnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqgla
fchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillg
ckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdy
kpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
r

Timeline for d2c4ga_:

• d2c4ga_ first appeared in SCOP 1.73, called d2c4ga1
  
• d2c4ga_ appears in SCOPe 2.02
  
• d2c4ga_ appears in SCOPe 2.04
  
• d2c4ga_ appears in the current release, SCOPe 2.08, called d2c4ga2