Lineage for d2bgda_ (2bgd A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2454571Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2454572Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2454684Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 2454728Protein Tyrosine phosphatase [52806] (7 species)
  7. 2454729Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (256 PDB entries)
    Uniprot P18031 2-300 ! Uniprot P18031 1-298 ! Uniprot P18031 2-299
  8. 2454854Domain d2bgda_: 2bgd A: [128474]
    automated match to d1suga_
    complexed with cl, na, po4, t1d

Details for d2bgda_

PDB Entry: 2bgd (more details), 2.4 Å

PDB Description: structure-based design of protein tyrosine phosphatase-1b inhibitors
PDB Compounds: (A:) protein-tyrosine phosphatase non-receptor type 1

SCOPe Domain Sequences for d2bgda_:

Sequence, based on SEQRES records: (download)

>d2bgda_ c.45.1.2 (A:) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d2bgda_ c.45.1.2 (A:) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}

SCOPe Domain Coordinates for d2bgda_:

Click to download the PDB-style file with coordinates for d2bgda_.
(The format of our PDB-style files is described here.)

Timeline for d2bgda_: