SCOP 1.73: Domain d2bexa1: 2bex A:5-460

Lineage for d2bexa1 (2bex A:5-460)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.10: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046] (3 superfamilies)
   2 curved layers, a/b; parallel beta-sheet; order 1234...N; there are sequence similarities between different superfamilies

4. Superfamily c.10.1: RNI-like [52047] (3 families)
   regular structure consisting of similar repeats

5. Family c.10.1.1: 28-residue LRR [52048] (2 proteins)
   this is a repeat family; one repeat unit is 1a4y A:207-235 found in domain

6. Protein Ribonuclease inhibitor [52049] (2 species)
   duplication: consists of 16 repeats

7. Species Human (Homo sapiens) [TaxId:9606] [52051] (4 PDB entries)

8. Domain d2bexa1: 2bex A:5-460 [128398]
   Other proteins in same PDB: d2bexc1, d2bexd1
   automatically matched to d1a4ya_
   complexed with gol, mak

Details for d2bexa1

PDB Entry: 2bex, 1.99 Å

PDB Description: crystal structure of placental ribonuclease inhibitor in complex with human eosinophil derived neurotoxin at 2a resolution

PDB Compounds: (A:) ribonuclease inhibitor

SCOP Domain Sequences for d2bexa1:

Sequence; same for both SEQRES and ATOM records:

>d2bexa1 c.10.1.1 (A:5-460) Ribonuclease inhibitor {Human (Homo sapiens) [TaxId: 9606]}
qsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalaelnlrs
nelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhlsdnll
gdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnndinea
gvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklgdvgma
elcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdegarllc
etllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvrelcqgl
gqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlvesvrqp
gclleqlvlydiywseemedrlqalekdkpslrvis

Timeline for d2bexa1:

• d2bexa1 is new in SCOP 1.73
  
• d2bexa1 appears in SCOP 1.75
  
• d2bexa1 appears in the current release, SCOPe 2.08, called d2bexa_