SCOPe 2.03: Domain d2baja_: 2baj A:

Lineage for d2baja_ (2baj A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase p38 [56129] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56130] (161 PDB entries)

8. Domain d2baja_: 2baj A: [128238]
   automated match to d1a9u__
   complexed with 1pp

Details for d2baja_

PDB Entry: 2baj, 2.25 Å

PDB Description: p38alpha bound to pyrazolourea

PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d2baja_:

Sequence, based on SEQRES records:

>d2baja_ d.144.1.7 (A:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
hhhsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrp
fqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivk
cqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtdde
mtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrl
vgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkrit
aaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppl

Sequence, based on observed residues (ATOM records):

>d2baja_ d.144.1.7 (A:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
hhhsqerptfyrqeliwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqs
iihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlndhvqfli
yqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyvatrwyrap
eimlnnqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesr
nyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpdd
epvadpydqsfesrdllidewksltydevisfvpppl

Timeline for d2baja_:

• d2baja_ first appeared in SCOP 1.73, called d2baja1
  
• d2baja_ appears in SCOPe 2.02
  
• d2baja_ appears in SCOPe 2.04
  
• d2baja_ appears in the current release, SCOPe 2.08, called d2baja2