SCOPe 2.04: Domain d2b55a_: 2b55 A:

Lineage for d2b55a_ (2b55 A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (340 PDB entries)
   Uniprot P24941

8. Domain d2b55a_: 2b55 A: [127877]
   automated match to d1aq1__
   complexed with d31

Details for d2b55a_

PDB Entry: 2b55, 1.85 Å

PDB Description: Human cyclin dependent kinase 2 (cdk2) complexed with indenopyraxole DIN-101312

PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d2b55a_:

Sequence, based on SEQRES records:

>d2b55a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records):

>d2b55a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkigvpstaireisllkelnhpnivkll
dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
lkpqnllintegaikladfgvvtlwyrapeillgckyystavdiwslgcifaemvtrral
fpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsl
lsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d2b55a_:

• d2b55a_ first appeared in SCOP 1.73, called d2b55a1
  
• d2b55a_ appears in SCOPe 2.03
  
• d2b55a_ appears in SCOPe 2.05
  
• d2b55a_ appears in the current release, SCOPe 2.08