Lineage for d2b4ro1 (2b4r O:4-152,O:319-335)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2843543Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
    family members also share a common alpha+beta fold in C-terminal domain
  6. 2843784Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [51801] (21 species)
  7. 2843882Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141916] (4 PDB entries)
    Uniprot Q8IKK7 4-152,319-335! Uniprot Q8T6B1 1-152,319-337
  8. 2843883Domain d2b4ro1: 2b4r O:4-152,O:319-335 [127845]
    Other proteins in same PDB: d2b4ro2, d2b4ro3, d2b4ro4, d2b4rp2, d2b4rp3, d2b4rp4, d2b4rq2, d2b4rq3, d2b4rq4, d2b4rr2, d2b4rr3, d2b4rr4
    complexed with aes, gol, nad

Details for d2b4ro1

PDB Entry: 2b4r (more details), 2.25 Å

PDB Description: crystal structure of glyceraldehyde-3-phosphate dehydrogenase from plasmodium falciparum at 2.25 angstrom resolution reveals intriguing extra electron density in the active site
PDB Compounds: (O:) glyceraldehyde-3-phosphate dehydrogenase

SCOPe Domain Sequences for d2b4ro1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2b4ro1 c.2.1.3 (O:4-152,O:319-335) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
tklgingfgrigrlvfraafgrkdievvaindpfmdlnhlcyllkydsvhgqfpcevtha
dgflligekkvsvfaekdpsqipwgkcqvdvvcestgvfltkelasshlkggakkvimsa
ppkddtpiyvmginhhqydtkqlivsnasXnewgysnrvldlavhit

SCOPe Domain Coordinates for d2b4ro1:

Click to download the PDB-style file with coordinates for d2b4ro1.
(The format of our PDB-style files is described here.)

Timeline for d2b4ro1: