SCOP 1.75: Domain d2axga1: 2axg A:182-276

Lineage for d2axga1 (2axg A:182-276)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Class I MHC, alpha-3 domain [88604] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88605] (157 PDB entries)
   Uniprot P30685 25-300
   Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor
   Uniprot P30481 25-300
   Uniprot P01892 25-298
   Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 alpha chain precursor
   Uniprot P30685 25-300 ! Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor ! Uniprot P30481 25-300 ! Uniprot P01892 25-298 ! Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 alpha chain precursor

8. Domain d2axga1: 2axg A:182-276 [127487]
   Other proteins in same PDB: d2axga2, d2axgb1
   automatically matched to d1a1ma1
   complexed with acy

Details for d2axga1

PDB Entry: 2axg, 2 Å

PDB Description: the immunogenicity of a viral cytotoxic t cell epitope is controlled by its mhc-bound conformation

PDB Compounds: (A:) HLA class I histocompatibility antigen, B*3501 heavy chain

SCOP Domain Sequences for d2axga1:

Sequence; same for both SEQRES and ATOM records:

>d2axga1 b.1.1.2 (A:182-276) Class I MHC, alpha-3 domain {Human (Homo sapiens) [TaxId: 9606]}
adppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrtf
qkwaavvvpsgeeqrytchvqheglpkpltlrwep

Timeline for d2axga1:

• d2axga1 first appeared in SCOP 1.73
  
• d2axga1 appears in SCOPe 2.01
  
• d2axga1 appears in the current release, SCOPe 2.08