Lineage for d2aw1a1 (2aw1 A:3-260)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 676371Fold b.74: Carbonic anhydrase [51068] (1 superfamily)
    single sheet; 10 strands
  4. 676372Superfamily b.74.1: Carbonic anhydrase [51069] (1 family) (S)
  5. 676373Family b.74.1.1: Carbonic anhydrase [51070] (1 protein)
  6. 676374Protein Carbonic anhydrase [51071] (10 species)
  7. 676402Species Human (Homo sapiens), erythrocytes, isozyme II [TaxId:9606] [51073] (197 PDB entries)
  8. 676416Domain d2aw1a1: 2aw1 A:3-260 [127388]
    automatically matched to d1can__
    complexed with cox, gol, hgb, zn

Details for d2aw1a1

PDB Entry: 2aw1 (more details), 1.46 Å

PDB Description: Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor Celecoxib
PDB Compounds: (A:) carbonic anhydrase II

SCOP Domain Sequences for d2aw1a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2aw1a1 b.74.1.1 (A:3-260) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnn
ghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvh
wntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprg
llpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvd
nwrpaqplknrqikasf

SCOP Domain Coordinates for d2aw1a1:

Click to download the PDB-style file with coordinates for d2aw1a1.
(The format of our PDB-style files is described here.)

Timeline for d2aw1a1: