SCOPe 2.08: Domain d2aq7c1: 2aq7 C:2-253

Lineage for d2aq7c1 (2aq7 C:2-253)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (3 families)

5. Family c.95.1.1: Thiolase-related [53902] (20 proteins)

6. Protein Beta-ketoacyl-ACP synthase I, N-terminal domain [419014] (2 species)

7. Species Escherichia coli [TaxId:562] [419486] (19 PDB entries)
   Uniprot P14926

8. Domain d2aq7c1: 2aq7 C:2-253 [127162]
   Other proteins in same PDB: d2aq7a2, d2aq7b2, d2aq7c2, d2aq7d2
   automated match to d1fj4a1
   complexed with tl5
   has additional insertions and/or extensions that are not grouped together

Details for d2aq7c1

PDB Entry: 2aq7, 2.3 Å

PDB Description: Structure-activity relationships at the 5-posiiton of thiolactomycin: an intact 5(R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherichia coli

PDB Compounds: (C:) 3-oxoacyl-[acyl-carrier-protein] synthase I

SCOPe Domain Sequences for d2aq7c1:

Sequence; same for both SEQRES and ATOM records:

>d2aq7c1 c.95.1.1 (C:2-253) Beta-ketoacyl-ACP synthase I, N-terminal domain {Escherichia coli [TaxId: 562]}
kravitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttglid
rkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadamr
gprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlgk
qdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvve
elehalargahi

Timeline for d2aq7c1:

• d2aq7c1 first appeared in SCOP 1.73
  
• d2aq7c1 appears in SCOPe 2.07