SCOPe 2.02: Domain d2amba_: 2amb A:

Lineage for d2amba_ (2amb A:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Androgen receptor [63621] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63623] (43 PDB entries)
   Uniprot P10275 671-919

8. Domain d2amba_: 2amb A: [127001]
   automated match to d1e3ga_
   complexed with 17h, dtt, epe, gol, so4

Details for d2amba_

PDB Entry: 2amb, 1.75 Å

PDB Description: Crystal structure of human androgen receptor ligand binding domain in complex with tetrahydrogestrinone

PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d2amba_:

Sequence, based on SEQRES records:

>d2amba_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpt
scsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgk
vkpiyfhtq

Sequence, based on observed residues (ATOM records):

>d2amba_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrtscs
rrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkp
iyfhtq

Timeline for d2amba_:

• d2amba_ first appeared in SCOP 1.73, called d2amba1
  
• d2amba_ appears in SCOPe 2.01
  
• d2amba_ appears in SCOPe 2.03
  
• d2amba_ appears in the current release, SCOPe 2.08