SCOP 1.73: Domain d2ajfa1: 2ajf A:19-615

Lineage for d2ajfa1 (2ajf A:19-615)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (15 families)

5. Family d.92.1.5: Neurolysin-like [55505] (4 proteins)
   combines M2, M3 and M32 families of metalloproteases
   the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

6. Protein Angiotensin converting enzyme 2, ACE2 [103125] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [103126] (3 PDB entries)

8. Domain d2ajfa1: 2ajf A:19-615 [126882]
   Other proteins in same PDB: d2ajfe1, d2ajff1
   automatically matched to d1r42a_
   complexed with bma, cl, nag, zn

Details for d2ajfa1

PDB Entry: 2ajf, 2.9 Å

PDB Description: structure of sars coronavirus spike receptor-binding domain complexed with its receptor

PDB Compounds: (A:) Angiotensin-converting enzyme-Related Carboxypeptidase (Ace2)

SCOP Domain Sequences for d2ajfa1:

Sequence; same for both SEQRES and ATOM records:

>d2ajfa1 d.92.1.5 (A:19-615) Angiotensin converting enzyme 2, ACE2 {Human (Homo sapiens) [TaxId: 9606]}
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

Timeline for d2ajfa1:

• d2ajfa1 is new in SCOP 1.73
  
• d2ajfa1 appears in SCOP 1.75
  
• d2ajfa1 appears in the current release, SCOPe 2.08, called d2ajfa_