SCOPe 2.07: Domain d2aeit2: 2aei T:109-209

Lineage for d2aeit2 (2aei T:109-209)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.2: Fibronectin type III [49265] (2 families)

5. Family b.1.2.1: Fibronectin type III [49266] (45 proteins)
   Pfam PF00041

6. Protein Extracellular region of human tissue factor [49267] (2 species)
   tandem of fibronectin type III domains

7. Species Human (Homo sapiens) [TaxId:9606] [49268] (35 PDB entries)
   Uniprot P13726 33-242

8. Domain d2aeit2: 2aei T:109-209 [126636]
   Other proteins in same PDB: d2aeih_, d2aeil1, d2aeil2, d2aeil3
   automatically matched to d1a21a2
   complexed with 03r, ca, cac

Details for d2aeit2

PDB Entry: 2aei, 2.52 Å

PDB Description: Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid

PDB Compounds: (T:) tissue factor

SCOPe Domain Sequences for d2aeit2:

Sequence, based on SEQRES records:

>d2aeit2 b.1.2.1 (T:109-209) Extracellular region of human tissue factor {Human (Homo sapiens) [TaxId: 9606]}
gqptiqsfeqvgtkvnvtvedertlvrrnntflslrdvfgkdliytlyywkssssgkkta
ktntneflidvdkgenycfsvqavipsrtvnrkstdspvec

Sequence, based on observed residues (ATOM records):

>d2aeit2 b.1.2.1 (T:109-209) Extracellular region of human tissue factor {Human (Homo sapiens) [TaxId: 9606]}
gqptiqsfeqvgtkvnvtvedertlvrrnntflslrdvfgkdliytlyywksgkktaktn
tneflidvdkgenycfsvqavipsrtvnrkstdspvec

Timeline for d2aeit2:

• d2aeit2 first appeared in SCOP 1.73
  
• d2aeit2 appears in SCOPe 2.06
  
• d2aeit2 appears in the current release, SCOPe 2.08