SCOPe 2.01: Domain d2a2qh_: 2a2q H:

Lineage for d2a2qh_ (2a2q H:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (28 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d2a2qh_: 2a2q H: [126052]
   Other proteins in same PDB: d2a2ql1, d2a2ql2, d2a2ql3, d2a2qt1, d2a2qt2
   automated match to d1cvwh_
   complexed with ca, cl, fuc, glc, mg, na, pbz, zn

Details for d2a2qh_

PDB Entry: 2a2q, 1.8 Å

PDB Description: complex of active-site inhibited human coagulation factor viia with human soluble tissue factor in the presence of ca2+, mg2+, na+, and zn2+

PDB Compounds: (H:) Coagulation factor VII

SCOPe Domain Sequences for d2a2qh_:

Sequence; same for both SEQRES and ATOM records:

>d2a2qh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d2a2qh_:

• d2a2qh_ first appeared in SCOP 1.73, called d2a2qh1
  
• d2a2qh_ was called d2a2qh1 in SCOP 1.75
  
• d2a2qh_ appears in SCOPe 2.02
  
• d2a2qh_ appears in the current release, SCOPe 2.08