SCOPe 2.05: Domain d2a1tc2: 2a1t C:9-241

Lineage for d2a1tc2 (2a1t C:9-241)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.6: Acyl-CoA dehydrogenase NM domain-like [56644] (1 superfamily)
   2 domains: (1) all-alpha: 5 helices; (2) contains an open beta-sheet barrel: n*=5, S*=8; complex topology

4. Superfamily e.6.1: Acyl-CoA dehydrogenase NM domain-like [56645] (3 families)
   flavoprotein: binds FAD; constituent families differ in the numbers of C-terminal domains (four-helical bundles)

5. Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains [56646] (10 proteins)

6. Protein automated matches [226961] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225392] (3 PDB entries)

8. Domain d2a1tc2: 2a1t C:9-241 [126010]
   Other proteins in same PDB: d2a1ta1, d2a1tb1, d2a1tc1, d2a1td1, d2a1tr1, d2a1tr2, d2a1ts1
   automated match to d1egda2
   complexed with amp, fad

Details for d2a1tc2

PDB Entry: 2a1t, 2.8 Å

PDB Description: structure of the human mcad:etf e165betaa complex

PDB Compounds: (C:) Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor

SCOPe Domain Sequences for d2a1tc2:

Sequence; same for both SEQRES and ATOM records:

>d2a1tc2 e.6.1.1 (C:9-241) automated matches {Human (Homo sapiens) [TaxId: 9606]}
glgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelglmnthipe
ncgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkkylgrmteep
lmcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyfllarsdpdpka
pankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvligd

Timeline for d2a1tc2:

• d2a1tc2 first appeared in SCOP 1.73
  
• d2a1tc2 appears in SCOPe 2.04
  
• d2a1tc2 appears in SCOPe 2.06
  
• d2a1tc2 appears in the current release, SCOPe 2.08