SCOPe 2.06: Domain d1zp8a_: 1zp8 A:

Lineage for d1zp8a_ (1zp8 A:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (476 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d1zp8a_: 1zp8 A: [125457]
   automated match to d3tlha_
   complexed with ab2

Details for d1zp8a_

PDB Entry: 1zp8, 2.02 Å

PDB Description: HIV Protease with inhibitor AB-2

PDB Compounds: (A:) Pol polyprotein

SCOPe Domain Sequences for d1zp8a_:

Sequence; same for both SEQRES and ATOM records:

>d1zp8a_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d1zp8a_:

• d1zp8a_ first appeared in SCOP 1.73, called d1zp8a1
  
• d1zp8a_ appears in SCOPe 2.05
  
• d1zp8a_ appears in SCOPe 2.07
  
• d1zp8a_ appears in the current release, SCOPe 2.08