Lineage for d1za6f2 (1za6 F:116-218)

  1. Root: SCOPe 2.05
  2. 1755445Class b: All beta proteins [48724] (176 folds)
  3. 1755446Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1755447Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1758822Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 1760578Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (6 species)
  7. 1760582Species Human (Homo sapiens) [TaxId:9606] [88575] (179 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3) ! SQ NA # humanized antibody ! Uniprot P01857 # IGHG1_HUMAN Ig gamma-1 chain C region ! SQ NA # engineered antibody
  8. 1760827Domain d1za6f2: 1za6 F:116-218 [124813]
    Other proteins in same PDB: d1za6a1, d1za6a2, d1za6b1, d1za6b3, d1za6c1, d1za6c2, d1za6d1, d1za6d3, d1za6e1, d1za6e2, d1za6f1, d1za6f3, d1za6g1, d1za6g2, d1za6h1, d1za6h3
    automatically matched to d1ngzb2

Details for d1za6f2

PDB Entry: 1za6 (more details), 2.8 Å

PDB Description: The structure of an antitumor CH2-domain-deleted humanized antibody
PDB Compounds: (F:) IGG Heavy chain

SCOPe Domain Sequences for d1za6f2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1za6f2 b.1.1.2 (F:116-218) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1za6f2:

Click to download the PDB-style file with coordinates for d1za6f2.
(The format of our PDB-style files is described here.)

Timeline for d1za6f2: