SCOPe 2.04: Domain d1z6el_: 1z6e L:

Lineage for d1z6el_ (1z6e L:)

1. Root: SCOPe 2.04

2. Class g: Small proteins [56992] (91 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein automated matches [190092] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187310] (66 PDB entries)

8. Domain d1z6el_: 1z6e L: [124519]
   Other proteins in same PDB: d1z6ea_
   automated match to d1g2lb_
   complexed with ik8

Details for d1z6el_

PDB Entry: 1z6e, 1.8 Å

PDB Description: Factor XA in complex with the inhibitor 1-(3'-amino-1,2-benzisoxazol-5'-yl)-n-(4-(2'-((dimethylamino)methyl)-1h-imidazol-1-yl)-2-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (razaxaban; DPC906; BMS-561389)

PDB Compounds: (L:) coagulation factor x

SCOPe Domain Sequences for d1z6el_:

Sequence; same for both SEQRES and ATOM records:

>d1z6el_ g.3.11.1 (L:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle

Timeline for d1z6el_:

• d1z6el_ first appeared in SCOP 1.73, called d1z6eb1
  
• d1z6el_ appears in SCOPe 2.03
  
• d1z6el_ appears in SCOPe 2.05
  
• d1z6el_ appears in the current release, SCOPe 2.08