Lineage for d1yy9a4 (1yy9 A:481-512)

  1. Root: SCOP 1.73
  2. 746751Class g: Small proteins [56992] (85 folds)
  3. 747016Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides
  4. 747642Superfamily g.3.9: Growth factor receptor domain [57184] (1 family) (S)
  5. 747643Family g.3.9.1: Growth factor receptor domain [57185] (5 proteins)
  6. 747644Protein EGF receptor Cys-rich domains [82887] (1 species)
  7. 747645Species Human (Homo sapiens) [TaxId:9606] [82888] (4 PDB entries)
  8. 747647Domain d1yy9a4: 1yy9 A:481-512 [124210]
    Other proteins in same PDB: d1yy9a1, d1yy9a2
    automatically matched to d1ivoa4
    complexed with bma, man, nag, ndg

Details for d1yy9a4

PDB Entry: 1yy9 (more details), 2.6 Å

PDB Description: Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
PDB Compounds: (A:) Epidermal growth factor receptor

SCOP Domain Sequences for d1yy9a4:

Sequence; same for both SEQRES and ATOM records: (download)

>d1yy9a4 g.3.9.1 (A:481-512) EGF receptor Cys-rich domains {Human (Homo sapiens) [TaxId: 9606]}
vchalcspegcwgpeprdcvscrnvsrgrecv

SCOP Domain Coordinates for d1yy9a4:

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Timeline for d1yy9a4: