SCOPe 2.01: Domain d1yxbd_: 1yxb D:

Lineage for d1yxbd_ (1yxb D:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.204: all-alpha NTP pyrophosphatases [101385] (1 superfamily)
   multihelical: dimeric 4-helical bundle surrounded by other helices; oligomerizes further in a tetramer

4. Superfamily a.204.1: all-alpha NTP pyrophosphatases [101386] (5 families)
   basic module consist of 5 active site-forming helices; four from one subunit/structural repeat; the fifth from the other subunit/repeat

5. Family a.204.1.4: HisE-like (PRA-PH) [140797] (1 protein)
   Pfam PF01503

6. Protein Phosphoribosyl-ATP pyrophosphatase HisE [140798] (5 species)

7. Species Streptomyces coelicolor [TaxId:1902] [140799] (1 PDB entry)
   Uniprot Q9EWK0 4-91

8. Domain d1yxbd_: 1yxb D: [124178]
   automated match to d1yxba1

Details for d1yxbd_

PDB Entry: 1yxb, 2.6 Å

PDB Description: Crystal structure of Phosphoribosyl-ATP pyrophosphatase from Streptomyces coelicolor. NESG target RR8.

PDB Compounds: (D:) Phosphoribosyl-ATP pyrophosphatase

SCOPe Domain Sequences for d1yxbd_:

Sequence, based on SEQRES records:

>d1yxbd_ a.204.1.4 (D:) Phosphoribosyl-ATP pyrophosphatase HisE {Streptomyces coelicolor [TaxId: 1902]}
ktfeelftelqhkaangdpatsrtaelvdkgvhaigkkvveeaaevwmaaeyegkdaaae
eisqllyhvqvmmvargislddvyahll

Sequence, based on observed residues (ATOM records):

>d1yxbd_ a.204.1.4 (D:) Phosphoribosyl-ATP pyrophosphatase HisE {Streptomyces coelicolor [TaxId: 1902]}
ktfeelftelqhkaantsrtaelvdkgvhaigkkvveeaaevwmaaeyegkdaaaeeisq
llyhvqvmmvargislddvyahll

Timeline for d1yxbd_:

• d1yxbd_ first appeared in SCOP 1.73, called d1yxbd1
  
• d1yxbd_ was called d1yxbd1 in SCOP 1.75
  
• d1yxbd_ appears in SCOPe 2.02
  
• d1yxbd_ appears in the current release, SCOPe 2.08, called d1yxbd2