SCOPe 2.08: Domain d1yt1a2: 1yt1 A:69-337

Lineage for d1yt1a2 (1yt1 A:69-337)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)

6. Protein HSP90 [55876] (3 species)

7. Species Dog (Canis familiaris) [TaxId:9615] [103225] (33 PDB entries)
   Uniprot P41148 76-285; Endoplasmin, GRP94

8. Domain d1yt1a2: 1yt1 A:69-337 [123989]
   Other proteins in same PDB: d1yt1a3, d1yt1b3
   automated match to d1u2oa_
   complexed with 1pe, pg4

Details for d1yt1a2

PDB Entry: 1yt1, 2.2 Å

PDB Description: crystal structure of the unliganded form of grp94, the er hsp90: basis for nucleotide-induced conformational change, grp94n(delta)41 apo crystal

PDB Compounds: (A:) Endoplasmin

SCOPe Domain Sequences for d1yt1a2:

Sequence, based on SEQRES records:

>d1yt1a2 d.122.1.1 (A:69-337) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
lreksekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalag
neeltvkikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqedgqst
seligqfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttit
lvlkeeasdyleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

Sequence, based on observed residues (ATOM records):

>d1yt1a2 d.122.1.1 (A:69-337) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
lreksekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalag
neeltvkikcdkeknllhvtdtgvgmtreelvknlgtigtseflnkmteaqeqstselig
qfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlke
easdyleldtiknlvkkysqfinfpiyvwssktktvwdwelmn

Timeline for d1yt1a2:

• d1yt1a2 first appeared in SCOP 1.73, called d1yt1a1
  
• d1yt1a2 appears in SCOPe 2.07