SCOPe 2.06: Domain d1y8tc2: 1y8t C:6-226

Lineage for d1y8tc2 (1y8t C:6-226)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.1: Prokaryotic proteases [50495] (16 proteins)

6. Protein Protease PepD [141383] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [141384] (2 PDB entries)
   Uniprot O53896 154-374
   Rv0983

8. Domain d1y8tc2: 1y8t C:6-226 [122768]
   Other proteins in same PDB: d1y8ta1, d1y8tb1, d1y8tc1
   automated match to d1y8ta2

Details for d1y8tc2

PDB Entry: 1y8t, 2 Å

PDB Description: Crystal Structure of RV0983 from Mycobacterium tuberculosis- Proteolytically active form

PDB Compounds: (C:) hypothetical protein Rv0983

SCOPe Domain Sequences for d1y8tc2:

Sequence, based on SEQRES records:

>d1y8tc2 b.47.1.1 (C:6-226) Protease PepD {Mycobacterium tuberculosis [TaxId: 1773]}
gsveqvaakvvpsvvmletdlgrqseegsgiilsaegliltnnhviaaaakpplgspppk
ttvtfsdgrtapftvvgadptsdiavvrvqgvsgltpislgsssdlrvgqpvlaigsplg
legtvttgivsalnrpvsttgeagnqntvldaiqtdaainpgnsggalvnmnaqlvgvns
aiatlgadsadaqsgsiglgfaipvdqakriadelistgka

Sequence, based on observed residues (ATOM records):

>d1y8tc2 b.47.1.1 (C:6-226) Protease PepD {Mycobacterium tuberculosis [TaxId: 1773]}
gsveqvaakvvpsvvmletdeegsgiilsaegliltnnhviaaaakpppkttvtfsdgrt
apftvvgadptsdiavvrvqgvsgltpislgsssdlrvgqpvlaigsplglegtvttgiv
salnrpvstqntvldaiqtdaainpgnsggalvnmnaqlvgvnsaiatlsgsiglgfaip
vdqakriadelistgka

Timeline for d1y8tc2:

• d1y8tc2 first appeared in SCOP 1.73
  
• d1y8tc2 appears in SCOPe 2.05
  
• d1y8tc2 appears in SCOPe 2.07
  
• d1y8tc2 appears in the current release, SCOPe 2.08