SCOPe 2.05: Domain d1x6va3: 1x6v A:34-228

Lineage for d1x6va3 (1x6v A:34-228)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.4: Adenosine-5'phosphosulfate kinase (APS kinase) [52572] (2 proteins)
   automatically mapped to Pfam PF01583

6. Protein Adenosine-5'phosphosulfate kinase (APS kinase) [52573] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142215] (3 PDB entries)
   Uniprot O43252 34-228

8. Domain d1x6va3: 1x6v A:34-228 [121757]
   Other proteins in same PDB: d1x6va1, d1x6va2, d1x6vb1, d1x6vb2
   complexed with adp, cl

Details for d1x6va3

PDB Entry: 1x6v, 1.75 Å

PDB Description: the crystal structure of human 3'-phosphoadenosine-5'-phosphosulfate synthetase 1

PDB Compounds: (A:) Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1

SCOPe Domain Sequences for d1x6va3:

Sequence, based on SEQRES records:

>d1x6va3 c.37.1.4 (A:34-228) Adenosine-5'phosphosulfate kinase (APS kinase) {Human (Homo sapiens) [TaxId: 9606]}
hvsrnkrgqvvgtrggfrgctvwltglsgagkttvsmaleeylvchgipcytldgdnirq
glnknlgfspedreenvrriaevaklfadaglvcitsfispytqdrnnarqihegaslpf
fevfvdaplhvceqrdvkglykkarageikgftgidseyekpeapelvlktdscdvndcv
qqvvellqerdivpv

Sequence, based on observed residues (ATOM records):

>d1x6va3 c.37.1.4 (A:34-228) Adenosine-5'phosphosulfate kinase (APS kinase) {Human (Homo sapiens) [TaxId: 9606]}
hvsrnkrgqvvgtrggfrgctvwltglsgagkttvsmaleeylvchgipcytldgdnirq
glnknlgfspedreenvrriaevaklfadaglvcitsfispytqdrnnarqihegaslpf
fevfvdaeyekpeapelvlktdscdvndcvqqvvellqerdivpv

Timeline for d1x6va3:

• d1x6va3 first appeared in SCOP 1.73
  
• d1x6va3 appears in SCOPe 2.04
  
• d1x6va3 appears in SCOPe 2.06
  
• d1x6va3 appears in the current release, SCOPe 2.08