SCOPe 2.04: Domain d1x0na_: 1x0n A:

Lineage for d1x0na_ (1x0n A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55564] (34 PDB entries)

8. Domain d1x0na_: 1x0n A: [121551]
   automated match to d1qg1e_
   complexed with dtf

Details for d1x0na_

PDB Entry: 1x0n

PDB Description: nmr structure of growth factor receptor binding protein sh2 domain complexed with the inhibitor

PDB Compounds: (A:) Growth factor receptor-bound protein 2

SCOPe Domain Sequences for d1x0na_:

Sequence; same for both SEQRES and ATOM records:

>d1x0na_ d.93.1.1 (A:) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
wffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdgagkyf
lwvvkfnslnelvdyhrstsvsrnqqiflrdieqvpqqpt

Timeline for d1x0na_:

• d1x0na_ first appeared in SCOP 1.73, called d1x0na1
  
• d1x0na_ was called d1x0na1 in SCOPe 2.03
  
• d1x0na_ appears in SCOPe 2.05
  
• d1x0na_ appears in the current release, SCOPe 2.08