SCOP 1.75: Domain d1wssh1: 1wss H:16-257

Lineage for d1wssh1 (1wss H:16-257)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (35 PDB entries)
   Uniprot P08709 213-466
   Uniprot P08709 213-446
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d1wssh1: 1wss H:16-257 [121238]
   Other proteins in same PDB: d1wssl1, d1wssl2, d1wssl3, d1wsst1, d1wsst2
   automatically matched to d1cvwh_
   complexed with 3cb, bgc, ca, fuc

Details for d1wssh1

PDB Entry: 1wss, 2.6 Å

PDB Description: human factor viia-tissue factor in complex with peptide-mimetic inhibitor that has two charged groups in p2 and p4

PDB Compounds: (H:) Coagulation factor VII

SCOP Domain Sequences for d1wssh1:

Sequence; same for both SEQRES and ATOM records:

>d1wssh1 b.47.1.2 (H:16-257) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d1wssh1:

• d1wssh1 first appeared in SCOP 1.73
  
• d1wssh1 is called d1wssh_ in SCOPe 2.01
  
• d1wssh1 appears in the current release, SCOPe 2.08, called d1wssh_