SCOPe 2.05: Domain d1t20a2: 1t20 A:1-181

Lineage for d1t20a2 (1t20 A:1-181)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
   dimeric

4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (2 families)

5. Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)

6. Protein Class I MHC, alpha-1 and alpha-2 domains [54468] (28 species)

7. Species Human (Homo sapiens), HLA-A2.1 [TaxId:9606] [54470] (92 PDB entries)
   Uniprot P01892 25-298

8. Domain d1t20a2: 1t20 A:1-181 [119125]
   Other proteins in same PDB: d1t20a1, d1t20b_
   automatically matched to d1akja2

Details for d1t20a2

PDB Entry: 1t20, 2.2 Å

PDB Description: Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-6I

PDB Compounds: (A:) HLA class I histocompatibility antigen, A-2 alpha chain

SCOPe Domain Sequences for d1t20a2:

Sequence; same for both SEQRES and ATOM records:

>d1t20a2 d.19.1.1 (A:1-181) Class I MHC, alpha-1 and alpha-2 domains {Human (Homo sapiens), HLA-A2.1 [TaxId: 9606]}
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
r

Timeline for d1t20a2:

• d1t20a2 first appeared in SCOP 1.73
  
• d1t20a2 appears in SCOPe 2.04
  
• d1t20a2 appears in SCOPe 2.06
  
• d1t20a2 appears in the current release, SCOPe 2.08