Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1221427Protein Tyrosine-protein kinase SYK [118131] (1 species)
    PTK group; SYK/ZAP-70 subfamily; non-membrane spanning protein tyrosine kinase
  7. 1221428Species Human (Homo sapiens) [TaxId:9606] [118132] (11 PDB entries)
    Uniprot P43405 363-635 # structure of the SH2 domain tandem region (9-265) is also known (55576)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1xba:
  2. Domain(s) for 1xbb:
    • 1221430Domain d1xbba_: 1xbb A: [115077]
      Structural genomics target
      complexed with sti
  3. Domain(s) for 1xbc:
    • 1221436Domain d1xbca_: 1xbc A: [115078]
      Structural genomics target
      complexed with stu
  4. Domain(s) for 3emg:
  5. Domain(s) for 3fqe:
  6. Domain(s) for 3fqh:
    1. 1221437Domain d3fqha_: 3fqh A: [175977]
      automated match to d1xbba_
      complexed with 057
    2. 1221438Domain d3fqhb_: 3fqh B: [175978]
      automated match to d1xbba_
      complexed with 057
  7. Domain(s) for 3fqs:
  8. Domain(s) for 3srv:
    1. 1221431Domain d3srva_: 3srv A: [185500]
      automated match to d1xbaa_
      complexed with gol, s19
    2. 1221432Domain d3srvb_: 3srv B: [185501]
      automated match to d1xbaa_
      complexed with gol, s19
  9. Domain(s) for 4dfl:
  10. Domain(s) for 4f4p:
  11. Domain(s) for 4fyo:

More info for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK: