SCOPe 2.02: Domain d1xtgb_: 1xtg B:

Lineage for d1xtgb_ (1xtg B:)

1. Root: SCOPe 2.02

2. Class h: Coiled coil proteins [57942] (7 folds)

3. Fold h.1: Parallel coiled-coil [57943] (34 superfamilies)
   this is not a true fold; includes oligomers of shorter identical helices

4. Superfamily h.1.15: SNARE fusion complex [58038] (1 family)
   tetrameric parallel coiled coil

5. Family h.1.15.1: SNARE fusion complex [58039] (11 proteins)

6. Protein Synaptosomal-associated protein SNAP-25 [88915] (3 species)
   provides up to two different helical regions to synaptic fusion complexes

7. Species Human (Homo sapiens) [TaxId:9606] [88917] (2 PDB entries)
   Uniprot P60880 146-204 # identical sequence to rat species

8. Domain d1xtgb_: 1xtg B: [116021]
   Other proteins in same PDB: d1xtga_
   complexed the catalytic domain of the botulinum neurotoxin
   complexed with cl, zn

Details for d1xtgb_

PDB Entry: 1xtg, 2.1 Å

PDB Description: crystal structure of neurotoxin bont/a complexed with synaptosomal- associated protein 25

PDB Compounds: (B:) synaptosomal-associated protein 25

SCOPe Domain Sequences for d1xtgb_:

Sequence; same for both SEQRES and ATOM records:

>d1xtgb_ h.1.15.1 (B:) Synaptosomal-associated protein SNAP-25 {Human (Homo sapiens) [TaxId: 9606]}
mdenleqvsgiignlrhmaldmgneidtqnrqidrimekadsnktrideanqratkmlg

Timeline for d1xtgb_:

• d1xtgb_ first appeared in SCOP 1.71
  
• d1xtgb_ appears in SCOPe 2.01
  
• d1xtgb_ appears in SCOPe 2.03
  
• d1xtgb_ appears in the current release, SCOPe 2.08